
The CPC Simulator tool, as the part of the CPC Modeler and also as an individual tool, lets you find the most effective CPC purification method and evaluate the productivity of your compound of interest. The core of the CPC Simulator consists of a database containing extensive data from scientific literature and a search engine that offers you purification methods tested with CPC. There are only two things needed to use the CPC Simulator: the partition coefficient and the composition of the crude material. The simulator lets you select between predefined instruments and separation modes. Several important factors affecting peak shape and separation performance are taken into account in the model calculations to improve the simulator's predictivity. These include high concentration, low solubility, and other factors. By changing a parameter's value, you get instant feedback on how it affects separation. As a result, the tool can give you the elution profile with a more precise estimation than a single partition coefficient value.
Find the most effective solvent system and purification method for CPC
Only two input data needed for operation: partition coefficient and composition of the crude material
Model, test and optimize purification performance
Estimate the elution profile with precision
Test thousands of compounds in silico to find future directions
Rely on a library of data from scientific literature, combined with an intelligent search engine, developed by chemists and chemoinformatic experts
Quick and cost-effective computational tests instead of slow, cumbersome and expensive experimentation
A library of extensive, well-researched and evolving data, instead of time-consuming literature search
Prediction-based results to support decision making

RotaChrom has developed the world’s first commercially available industrial scale centrifugal partition chromatography (CPC) platform. This technology revolutionized the purification industry by providing cost-effective commercial scale chromatographic solutions to Partners all over the world. RotaChrom is currently working with a broad array of industries including pharmaceutical, nutraceutical, health and beauty, and botanical companies, CROs, CDMOs, research and academia, and more in the Americas, Europe, China, India, and Asia.
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Limited access to our partition database
Limited access to compound details
Search by compound name, SMILES or CAS number
Unlimited access to our database
Search by compound name, SMILES or CAS number
Search by chemical structure and similarity (by Chemaxon)
List all compound details
Simulate CPC separation